D-mannose worked about as well as the antibiotic nitrofurantoin for preventing UTIs over a 6-month period. In a 2014 study, D-mannose was compared to the antibiotic trimethoprim/sulfamethoxazole for treatment and prevention of frequent UTIs in 60 women. D-mannose reduced UTI symptoms in women with an active infection.

How long does it take for D-mannose to cure UTI?

Overall, our results support the conclusion that the clinical regimen of d-mannose applied to treat acute UTIs (3 g/day for three days, then 1.5 g/day for 10 days, [31]) does not lead to FimH mutations that modify bacterial adhesiveness.

Does D-mannose really work for UTI?

A 2014 study in the World Journal of Urology found that D-mannose may be effective in preventing people from getting further UTIs after they have recovered from one. In the study, D-mannose was slightly more effective than the antibiotic Nitrofurantoin.