No. After the destruction of the ring and his body yet again destroyed his spirit is render impotent. He will always be there, but never again to take a physical form.

Is Sauron coming back again?

ANSWER: J.R.R. Tolkien all but completely ruled out the possibility that Sauron might return as a Dark Lord to trouble Middle-earth. Sauron had placed most of his “native strength” in the Ring, and when the Ring was destroyed Sauron was reduced to an extremely weak spirit incapable of taking physical shape again.

How long did it take for Sauron to return?

I've been wondering if there is some explanation in the books (Unfinished Tales, HoME) as to why Sauron needs so much time in order to recover his strength after Isildur cut the One Ring from his hand. There are over 3000 years passing between the end of the Second Age and the War of the Ring.