Nutritional yeast should be stored in a cool, dark place to preserve its vitamins. It should also be kept tightly sealed to keep moisture out. When properly stored, it can last up to two years.
Can I eat expired nutritional yeast?
It's unlikely for unopened nutritional yeast to go bad unless you expose it to high heat or moisture. That said, the shelf life of nutritional yeast is only about 24 months, so it would still be unadvised to eat it beyond that point, even if it was unopened.
How long does nutritional yeast keep?
Since it's a dry product, you want to lid tightly sealed to keep moisture out — as long as nutritional yeast stays dry, it can last for up to two years.