The MITOGEN-NIL value serves as the positive control for the patient specimen, demonstrating successful lymphocyte activity. The TB1-NIL tube specifically detects CD4+ lymphocyte reactivity, specifically stimulated by the TB1 antigens.
What does Mitogen nil mean?
Mitogen-Nil The maximum non-specific stimulated interferon- gamma level that may be produced by the patient's lymphocytes minus the Nil (i.e., basal) level of interferon-gamma. (The reporting range for the Nil is 0 - >8.0.
What is a normal Mitogen nil?
The NIL tube value indicates if the patient has an ongoing immune response which can cause a false-positive result. The NIL tube must be ≤ 8.0 IU/mL. Significance of the MITOGEN result: The mitogen control tube addresses the immune competence of the patient's immune cells to produce interferon-γ.