Mitsuki was created as a synthetic human by Orochimaru, being cultivated from the same embryo as at least one older "Mitsuki". ... Upon discovering the existence of Boruto Uzumaki via a gift from Orochimaru, Mitsuki decided to go to Konoha and befriend him in order to find his own path in life.

How did Orochimaru make Mitsuki?

As no one wants to romantically entangle themselves with the snake Sannin, his son was created as a clone. Except, Mitsuki isn't exactly a full clone. Orochimaru experimented, spliced, and scrambled his genetics to make them as perfect as possible. Best put, Mitsuki is an artificial being.

Who is Mitsuki's real parents?

Mitsuki was created as a synthetic human by Orochimaru. It has been revealed in Boruto: Naruto the Movie that, Mitsuki is Orochimaru's son. In the movie, Boruto questions Mitsuki about his parentage to which Mitsuki replies that he is the son of Orochimaru.