RNase P is found in cells from all three domains of life: the Bacteria, Eukarya and Archaea. It contains a highly conserved catalytic RNA component — a unique, natural ribozyme that conducts multiple turnovers with a broad substrate specificity.

Where is RNase a found?

What is RNase A? Ribonuclease A is a digestive enzyme secreted by the pancreas that specifically "digests" or hydrolyzes RNA (but not DNA) polymers by endonuclease cleavage of the phosphodiester bonds forming the covalent links between adjacent ribonucleotide residues in these molecules.

What does RNase P do?

Ribonuclease P (RNase P) is an endoribonuclease that cleaves other RNA molecules at the junction between a single-stranded region and the 5′ end of a double-stranded region.