Promethazine was made in the 1940s by a team of scientists from Rhône-Poulenc laboratories. It was approved for medical use in the United States in 1951. It is a generic medication and is available under many brand names globally.

What generation is promethazine?

Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects.

Do they still prescribe promethazine?

Recently, pharmaceutical company Actavis decided to pull their very popular prescription-only cough and cold medication, promethazine with codeine syrup, off the market. The discontinuation of this product is due to the popularity of its recreational use.