Significance. A knowledge of the CMC is very important when using surfactants. ... When the formation of micelles is desirable, e.g. when cleaning, the CMC is a measure of the efficiency of a surfactant. Variables for the scientific characterisation of the surface adsorption can also be derived from the CMC.

What is the importance of CMC in pharmacy?

CMC can become useful to guide drug discovery scientists to better diagnose, improve, and predict solubility in biorelevant media, thereby enhancing oral bioavailability of drug candidates.

What is the role of the critical micelle concentration?

Another important characteristic is the critical micelle concentration (CMC), which is defined as the concentration of surfactants when the micelles spontaneously form. The addition of surfactant reduces the interface energy and removes the hydrophobic groups of the surfactant from contact with water (Fig.