In the last scene of the play, 5.2, Brabantio's brother Graziano states that Brabantio died of grief after losing his daughter to Othello.

What happened to Brabantio in Act 5?

Gratiano then announces that it's a good thing Desdemona's dad, Brabantio, died of heartbreak over her wedding to Othello, because he really wouldn't have survived this traumatic event. ... Othello, furious, tries to stab Iago, but Iago avoids him, and instead stabs his wife to death (seemingly), and runs out.

What happens in Act 5 Scene 2 of Othello?

Summary: Act V, scene ii. Holding a candle, Othello stands over the sleeping Desdemona and prepares to kill her. He bends down to kiss her once before he does the deed, she wakes, and he tells her to prepare to die. ... Othello asks if Cassio has been killed as well, and Emilia informs him that Cassio is alive.