Acanthosis nigricans is a condition that may become apparent at any age. Many benign forms develop during childhood or puberty, while the onset of malignant AN, most frequently occurs after 40 years of age.

What can cause acanthosis?

Acanthosis nigricans skin patches occur when epidermal skin cells begin to reproduce rapidly. This abnormal skin cell growth is most commonly triggered by high levels of insulin in the blood. In rare cases, the increase in skin cells may be caused by medications, cancer, or other medical conditions.

What causes epidermal acanthosis?

Acanthosis nigricans often occurs in people who have disorders such as ovarian cysts, underactive thyroids or problems with the adrenal glands. Certain drugs and supplements. High-dose niacin, birth control pills, prednisone and other corticosteroids may cause acanthosis nigricans.