Which antibiotic is best for mastoiditis?
Antibiotic selection should provide good intracranial penetration and MDRSP coverage. With the high frequency of invasive resistant strains in mastoiditis, initial therapy of intravenous vancomycin and ceftriaxone is most appropriate until results of the culture and sensitivity studies are available.
Can mastoiditis be treated with oral antibiotics?
Chronic mastoiditis is treated with oral antibiotics, eardrops, and regular ear cleanings by a doctor. If these treatments do not work, surgery may be necessary to prevent further complications.