An adequate supply of certain B vitamins are necessary for a healthy methylation cycle to occur. Vitamins B2, B6 and B12 are needed for the activity of particular enzymes used by this cycle. Folate (vitamin B9) is a vital nutrient which helps to produce methyl groups which in turn helps methylation to take place.

Which B vitamins should be methylated?

To regulate homocysteine levels, the body requires methylated forms of vitamins B12, B6 & folate. Dietary intake of these necessary nutrients may not be converting to the active forms due to genetic variants on the MTHFR gene.

What are methylated B vitamins good for?

In addition to maintaining DNA repair, methylation reactions help maintain optimal neurotransmitter production, homocysteine balance for cardiovascular health, recycle molecules that are required for detoxification and support a healthy inflammatory response.