Intestinal pseudo-obstruction is often not inherited, and most affected individuals do not have a family history of the disorder. When it does run in families, it can have different inheritance patterns. Intestinal pseudo-obstruction caused by FLNA gene mutations is inherited in an X-linked recessive pattern .
What is the most common cause of small bowel obstruction?
Small bowel obstructions are usually caused by scar tissue, hernia, or cancer. In the United States, most obstructions occur as a result of prior surgeries. The bowel often forms bands of scar (called adhesions) after being handled during an operation.
What puts you at risk for a bowel obstruction?
Some risk factors associated with SBO include the following: Previous abdominal or pelvic surgery, previous radiation therapy, or both: May be part of the patient's medical history. History of malignancy: Particularly ovarian and colonic malignancy. Inflammatory bowel disease.