Granulation tissue is considered a contractile organ, characterized histologically by the presence and proliferation of fibroblasts, keratinocytes, endothelial cells, new thin-walled capillaries, and inflammatory cell infiltration of the extracellular matrix.

What does granulation of tissue mean?

Granulation tissue is vascularized tissue that forms as chronic inflammation evolves. The new capillaries make the tissue appear pink and granular, thus the name. Histologically, one can observe macrophages and proliferating fibroblasts within granulation tissue.

What does granulation mean in a wound?

What Does The Presence of Granulation Tissue Mean? In short, observing granulation tissue in the bed of the wound means that the wound is progressing from the inflammatory phase of healing to the proliferative phase of healing. Several important cellular developments are occurring.